Insights

Cobalt-catalyzed C–H activation in organic synthesisCobalt-catalyzed C–H activation lets organic chemists build bonds directly on unmodified carbon frameworks. By converting a C–H site into a C–C or C–heteroatom…
Gold nanoparticles for combined cancer treatment and imagingGold nanoparticles as theranostic agents in cancer occupy a promising boundary between laboratory nanoscience and translational oncology. By combining…
Magnesium, RNA and Australia's bioscience futureThe 16th International Symposium on Applied Bioinorganic Chemistry (ISABC) was held in Ioannina, Greece, in June 2023. Organised by the University of Ioannina,…
Designing artificial metalloenzymes for green chemistryArtificial metalloenzymes combine a tailored protein scaffold with a metal centre, creating biocatalysts that can approach the selectivity of enzymes while…
Ruthenium Photosensitizers and the Future of Photodynamic TherapyPhotodynamic therapy (PDT) is an emerging treatment strategy that combines a light-activated compound, a suitable wavelength and molecular oxygen to damage…
Molybdenum enzymes in the global nitrogen cycleThe 16th International Symposium on Applied Bioinorganic Chemistry (ISABC) was held in Ioannina, Greece, in June 2023, organised by the University of Ioannina.…
Copper homeostasis and neurodegenerative diseases at ISABC 2023Copper is a trace metal with an outsized role in neuronal energy production, antioxidant defence and synaptic signalling. At the 16th International Symposium…
Zinc finger proteins in gene regulation and drug designZinc finger proteins are compact molecular readers that help cells interpret DNA and RNA with remarkable precision. Their zinc-dependent architecture links…
Platinum anticancer drugs: mechanisms and resistancePlatinum anticancer drugs remain a benchmark in cancer treatment because their DNA-damaging activity can produce durable responses in several tumour types.…
Recent advances in iron–sulfur cluster biosynthesisThe 16th International Symposium on Applied Bioinorganic Chemistry gathered researchers in Ioannina, Greece, in June 2023 to examine how cells construct and…